Season 1
The season's sub-plot revolved around billionaire Edward Vogler making a $100 million donation to the hospital. Through this donation, Vogler became the new chairman of the board of PPTH, however, seeing House and his team as a waste of time and resources, he decreases their payment, eventually forcing House to fire one of his team members.
Season 2
During the season, House tries to cope with his feelings for his ex-girlfriend Stacy Warner, who, after House diagnosed her husband with Acute intermittent porphyria, has taken a job in the legal department of the PPTH. Sela Ward's chemistry with Laurie in the final two episodes of season one was strong enough to have her character return in seven episodes of the second season.
Season 3
Early in the season, House temporarily regains the use of his leg, due toKetamine treatment, after he was shot in the season two finale. Later in the season, he leaves a stubborn patient in an exam room with a thermometer in his rectum. Because House is unwilling to apologize, the patient, police detective Michael Tritter, starts an investigation to uncover House's vicodin addiction. The third season concluded with a cliffhanger finale, in which House fires Chase, and Foreman and Cameron both resign, leaving House without a team for the fourth season.
Season 4
Having previously fired Chase, and with Foreman and Cameron quitting, House starts a competition between forty applicants for the vacant positions. He eventually narrows them down to seven, firing one each episode. In the episode "Games", he fires Amber "Cutthroat Bitch" Volakis (Anne Dudek), hiring Dr. Chris Taub (Peter Jacobson), Dr. Lawrence Kutner (Kal Penn) and Dr. Remy "Thirteen" Hadley (Olivia Wilde) as his new team. Dr. Foreman rejoins the team after his dismissal from another hospital. Meanwhile, Amber begins a relationship with Wilson.
Season 5
The fifth season of House premiered September 16, 2008 and ended May 11, 2009. It began to air in a new time slot from September to December: Tuesday 8/7c. Starting January 19, 2009, House moved to Mondays at 8/7c. Sky1 has taken over the rights to screen the show in the UK airing Sundays at 9pm.
Season 6
House entered a sixth season on September 21, 2009 with a two-hour premiere. The season premiere, titled "Broken", was filmed at theGreystone Park Psychiatric Hospital in New Jersey.
Season six featured 22 episodes, two fewer than the usual number. In the United Kingdom, the series began airing on Sky 1 and Sky 1 HD on October 4, 2009, two weeks behind the North American broadcast.
Season six featured 22 episodes, two fewer than the usual number. In the United Kingdom, the series began airing on Sky 1 and Sky 1 HD on October 4, 2009, two weeks behind the North American broadcast.
Season 7
Dr. House and Cuddy attempt to make a real relationship work and face the question as to whether their new relationship will affect their ability to diagnose patients. The new season features a new opening title sequence. This is the first change in the opening sequence since the show began; Jennifer Morrison's name has been removed from the credits, while Peter Jacobson's and Olivia Wilde's have been added to it, with new background images also inserted into the traditional title sequence.
Season 8
It was announced that David Shore would direct and co-write the final episode of the show and also that Olivia Wilde would return as Thirteen for the penultimate episode and the series finale. Confirmed sources have also stated that Lisa Edelstein would not be returning for the series finale. Kal Penn was reported to be in talks and returned as Dr. Kutner. Amber Tamblyn also came back as Martha M. Masters for the finale. Jennifer Morrison appeared in the finale in a cameo appearance as Allison Cameron. Anne Dudek, Sela Ward and Andre Braugher also reprised their previous recurring/guest roles as Amber Volakis, Stacy Warner, and Darryl Nolan respectively. The series finale aired on May 21 following a retrospective episode titled "Swan Song."